PRKAA1

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolPRKAA1
Nameprotein kinase AMP-activated catalytic subunit alpha 1
Typeprotein-coding
Sourcemygene

Summary

The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP

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