| Gene Symbol | PRKAA1 |
| Full Name | Protein Kinase AMP-Activated Catalytic Subunit Alpha 1 (AMPKα1) |
| Chromosome | 5p13.1 |
| Protein Type | Kinase |
| Target Class | Kinase |
| Function | Small molecule activator of AMP-activated protein kinase |
| Mechanism of Action | Small molecule activator of AMP-activated protein kinase |
| Druggability | Medium (0.55) |
| Clinical Stage | Approved |
| Amino Acids | 559 aa |
| Exons | 10 |
| Pathways | AMPK |
| UniProt ID | Q13131 |
| Ensembl ID | ENSG00000132356 |
| GeneCards | PRKAA1 |
| Human Protein Atlas | PRKAA1 |
| Associated Diseases | Als, Alzheimer, Alzheimer's disease |
| Known Drugs/Compounds | metformin, Metformin |
| Interactions | AKT, ALZHEIMER, ALZHEIMER'S DISEASE, AMPK, AMYLOID, AND |
| SciDEX Target | View Target Profile (8 clinical trials) |
| SciDEX Hypotheses | AMPK hypersensitivity in astrocytes creates enhanc |
| KG Connections | 584 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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