Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about Palmitoylation: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
Knowledge base pages for this entity
| Target | Relation | Type | Str |
|---|---|---|---|
| RIPK1 | activates | protein | 0.90 |
| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| Hippocampal CA3-CA1 synaptic rescue via DHHC2-mediated PSD95 | 0.695 | Alzheimer's disease | Circuit-level neural dynamics in neurode |
| Palmitoylation-Targeted BACE1 Trafficking Disruptors | 0.407 | neurodegeneration | Lipid raft composition changes in synapt |
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| Machine Learning and Novel Biomarkers for the Diagnosis of Alzheimer's Disease. [PMID:33803217] | Chang CH, Lin CH, Lane HY | Int J Mol Sci | 2021 | 1 |
| Blocking palmitoyl-transferase activity reduces BACE1 membrane localization and [PMID:23395894] | Unknown | Molecular Neurodegeneration | 0 | |
| Amyloid-β fibrils accumulated in preeclamptic placentas suppress cytotrophoblast [PMID:41558820] | Nishioka K, Ikezaki M, Iwahashi N, Araka | Life Sci Alliance | 2026 | 0 |
| An anti-inflammatory neuroenhancer mitigates amyloid-β pathology to improve Alzh [PMID:41696149] | Fang W, Zhao J, Li L, Wang Y, Xu ZP et a | Mater Today Bio | 2026 | 0 |
| Anti-ASC antibodies alleviate Alzheimer's disease-type pathology in APP/PS1 mice [PMID:41707905] | He L, Xiaopeng Z, Juan D, Yan L | Neuroscience | 2026 | 0 |
| Intranasal administration of neural stem cell-derived extracellular vesicles pre [PMID:41923110] | Natale F, Dellaria A, Nifo Sarrapochiell | Alzheimer's research & therapy | 2026 | 0 |
| Salvianolic acid a inhibits neuroinflammation and ameliorates Alzheimer's diseas [PMID:41930874] | Xiao S, Han Y, Yan J, Wu L, Lin H et al. | Int Immunopharmacol | 2026 | 0 |
| Repurposing FDA-approved drugs as multi-target neuroprotective agents for Alzhei [PMID:41946775] | Phemphunananchai K, Waiwut P, Phetcharab | Scientific reports | 2026 | 0 |
| Nano-magnolol enhances the modulatory effects of magnolol on cognitive performan [PMID:41954680] | Youssef B, Ibrahim EA, Moselhy SS, ElShe | Discov Nano | 2026 | 0 |
| BACE-1 inhibitors as potential drug candidates for treatment of Alzheimer's dise [PMID:41966670] | Kaur N, Gupta S, Bansal G, Bansal Y | Mol Divers | 2026 | 0 |
| Alzheimer's disease basics: we all should know. [PMID:40639927] | Das S | Neurological research | 2026 | 0 |
| Demethyleneberberine attenuates combined cognitive and metabolic dysfunctions in [PMID:41482106] | Kaur A, Singh S, Singh M, Silakari P, Ma | Experimental neurology | 2026 | 0 |
| Zhi-Gan Formula improved insomnia and anxiety comorbidity in a mouse model via P [PMID:41525914] | Liu R, Wu Z, Yin Y, Song C, Zhang C et a | J Ethnopharmacol | 2026 | 0 |
| Triterpenoid saponins from Platycodon grandiflorus exhibit antidepressant-like e [PMID:41539634] | Yoon S, Chun E, Iqbal H, Kim SH, Kim SY | J Ethnopharmacol | 2026 | 0 |
| Integrative GWAS identifies novel loci and genetic links between psychiatric and [PMID:41927769] | Song Y, Jiang Y, Tian H, Glessner J, Hak | Mol Psychiatry | 2026 | 0 |
| Designed Liquid Crystalline Nanoassemblies From Clinically Validated Polyunsatur [PMID:41937329] | Akanchise T, Luo F, Angelov B, Deng Y, A | Adv Healthc Mater | 2026 | 0 |
| Single transient exposure to low-frequency low-intensity electrical stimulation [PMID:41942002] | Marcotto GS, Borghetti M, Bitraj J, Cava | Neuropharmacology | 2026 | 0 |
| Serpina1e mediates the exercise-induced enhancement of hippocampal memory in mal [PMID:41957371] | Kim H, Shin S, Han J, Yun K, Kim JS et a | Nat Commun | 2026 | 0 |
| Ubiquinol Ameliorates Social Disruption-induced Behavioral Changes via Modulatin [PMID:41962635] | Chen CW, Huang BR, Yeh WL, Huang SS, Cha | Behav Brain Res | 2026 | 0 |
| Dietary Advanced Glycation End Products Induced Anxiety- and Depression-like Beh [PMID:41962780] | Ma T, He Z, Yang G, Cai J, Qin LQ et al. | J Nutr Biochem | 2026 | 0 |