Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about Prolonged Anesthesia: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Target | Relation | Type | Str |
|---|---|---|---|
| Neuroinflammation | causes | process | 0.95 |
| Perioperative Neurocognitive Disorders | risk_factor_for | disease | 0.90 |
| Perioperative Neurocognitive Disorder | causes | disease | 0.90 |
| Anxiety-like Behaviors | associated_with | phenotype | 0.85 |
| Neuronal Excitability | inhibits | process | 0.80 |
| microglial territorial disruption | causes | phenotype | 0.70 |
| synapse vulnerability to complement | causes | phenotype | 0.70 |
| ER stress in vulnerable neurons | causes | phenotype | 0.70 |
| P2Y12 downregulation | causes | phenotype | 0.70 |
| synaptic elimination | increases_risk | phenotype | 0.70 |
| microglial territorial organization | disrupts | phenotype | 0.70 |
| P2Y12 expression | inhibits | protein | 0.70 |
| Source | Relation | Type | Str |
|---|---|---|---|
| Neurocognitive Dysfunction | associated_with | phenotype | 0.70 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
synaptic biology | 2026-04-07 | 17 hypotheses Top: 0.833
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
Hypotheses and analyses mentioning Prolonged Anesthesia in their description or question text
No additional research found