gene

RAB22A

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about RAB22A: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

RAB22A - Member RAS Oncogene Family - A small GTPase involved in endocytic trafficking and early endosome organization

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🧬 Gene Info

Gene Symbol	RAB22A
Full Name	Member RAS Oncogene Family
Chromosome	20q13.32
Function	is a small GTPase belonging to the RAB GTPase family that plays critical roles in endocytic trafficking and early endosome organization.
Molecular Weight	24 kDa
Amino Acids	213 aa
UniProt ID	Q9H832
NCBI Gene ID	57403
Ensembl ID	ENSG00000027869
OMIM	605241
GeneCards	RAB22A
Human Protein Atlas	RAB22A
G1 motif (P-loop)	Nucleotide binding site
G2 motif	Switch region I, undergoes conformational change upon GTP binding
G3 motif	Switch region II, critical for effector interactions
Associated Diseases	neurodegeneration
Databases	GeneCards HPA STRING

🔮 Predicted Structure: RAB22A — AlphaFold Q9H832 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

RAB22A

gene · 2337 words

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Pathway Diagram

graph TD
    RAB22A["RAB22A"]
    neurodegeneration["neurodegeneration"]
    RAB22A -->|"implicated_in"| neurodegeneration
    style RAB22A fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
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Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity