Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about RAD23B: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | RAD23B |
| Full Name | RAD23 Homolog B |
| Chromosome | 9q31.2 |
| Function | RAD23B is a homolog of RAD23A with overlapping functions in nucleotide excision repair (NER) and the ubiquitin-proteasome system. |
| Primary Expression | all brain regions, with highest expression in the hippocampus and cerebral cortex |
| Molecular Weight | 43 kDa |
| Amino Acids | 409 aa |
| UniProt ID | P54727 |
| NCBI Gene ID | 5887 |
| Ensembl ID | ENSG00000132639 |
| OMIM | 600061 |
| GeneCards | RAD23B |
| Human Protein Atlas | RAD23B |
| Associated Diseases | neurodegeneration |
| KG Connections | 2 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
Knowledge base pages for this entity
graph TD
RAD23B["RAD23B"]
TREM2["TREM2"]
RAD23B -->|"upregulates"| TREM2
TP53["TP53"]
RAD23B -->|"binds"| TP53
neurodegeneration["neurodegeneration"]
RAD23B -->|"implicated in"| neurodegeneration
style RAD23B fill:#1a237e,stroke:#4fc3f7,color:#4fc3f7| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
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| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
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| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning RAD23B in their description or question text
No additional research found