Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about RPL13A: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
Gene profile: RPL13A - a component of the 60S ribosomal subunit involved in protein synthesis and translational control
No AI portrait yet
| Gene Symbol | RPL13A |
| Full Name | Ribosomal Protein L13A |
| Aliases | Gene profile: RPL13A |
| Chromosome | 19q13.3 |
| Function | The ribosome is the cellular machinery responsible for protein synthesis (translation), reading mRNA sequences and assembling amino acids into polypeptide chains. |
| Primary Expression | both neurons and glial cells, consistent with its fundamental role in cellular protein synthesis |
| UniProt ID | P32969 |
| NCBI Gene ID | 6145 |
| Ensembl ID | ENSG00000067533 |
| GeneCards | RPL13A |
| Human Protein Atlas | RPL13A |
| Associated Diseases | neurodegeneration |
| KG Connections | 1 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
Knowledge base pages for this entity
flowchart TD
N0["RPL13A"]
N1["GAPDH"]
N1 -->|"expressed in"| N0
N2["neurodegeneration"]
N0 -->|"implicated in"| N2
classDef gene fill:#1a3a2a,stroke:#4caf50,color:#e0e0e0
classDef protein fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
classDef disease fill:#3a1a1a,stroke:#ef5350,color:#e0e0e0
classDef pathway fill:#2a1a3a,stroke:#ce93d8,color:#e0e0e0
classDef mechanism fill:#2a2a1a,stroke:#ffd54f,color:#e0e0e0
class N1 gene| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| GAPDH | expressed_in | gene | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning RPL13A in their description or question text
No additional research found