GAPDH

Understanding Entity Pages

This page aggregates everything SciDEX knows about GAPDH: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

GAPDH is a gene implicated in neurodegeneration research. Key relationships include: associated with, regulates, inhibits. Associated with ALS, Aging, Als. Connected to 581 entities in the SciDEX knowledge graph.

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flowchart TD
    GAPDH(["GAPDH"])
    Als["Als"]
    glycolysis["glycolysis"]
    IFN_gamma_mRNA(["IFN-gamma mRNA"])
    IFN_gamma(["IFN-gamma"])
    Glycolysis["Glycolysis"]
    Neurodegeneration["Neurodegeneration"]
    Parkinson["Parkinson"]
    Cancer["Cancer"]
    Tumor["Tumor"]
    Aging["Aging"]
    Mtor["Mtor"]

    GAPDH -->|"activates"| Als
    GAPDH -->|"participates in"| glycolysis
    GAPDH -->|"interacts with"| IFN_gamma_mRNA
    GAPDH -->|"regulates"| IFN_gamma
    glycolysis -->|"regulates"| GAPDH
    GAPDH -->|"regulates"| Glycolysis
    GAPDH -->|"activates"| Neurodegeneration
    GAPDH -->|"associated with"| Parkinson
    GAPDH -->|"regulates"| Cancer
    GAPDH -->|"regulates"| Tumor
    GAPDH -.->|"inhibits"| Neurodegeneration
    GAPDH -->|"regulates"| Aging
    GAPDH -->|"activates"| Aging
    GAPDH -->|"therapeutic target"| Cancer
    GAPDH -->|"associated with"| Mtor

    style GAPDH fill:#006494,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0