gene

RPL27

Entity Detail — Knowledge Graph Node

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This page aggregates everything SciDEX knows about RPL27: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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🧬 Gene Info

Gene Symbol	RPL27
Full Name	Ribosomal Protein L27
Chromosome	17q.
Function	is a component of the 60S large ribosomal subunit and is encoded by the RPL27 gene located on chromosome 17q.
UniProt ID	P61353
NCBI Gene ID	6157
Ensembl ID	ENSG00000131469
OMIM	604199
GeneCards	RPL27
Human Protein Atlas	RPL27
tRNA binding	Accommodates peptidyl-tRNA and aminoacyl-tRNA
Peptide bond formation	Catalyzes the formation of peptide bonds
Translocation	Moves the ribosome along the mRNA
Pro-apoptotic effects	Under certain stress conditions
Anti-apoptotic effects	Via p53-independent pathways
Associated Diseases	neurodegeneration
Databases	GeneCards HPA STRING

🔮 Predicted Structure: RPL27 — AlphaFold P61353 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

RPL27 — Ribosomal Protein L27

gene · 1806 words

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RPL27A — Ribosomal Protein L27A

gene · 2204 words

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Pathway Diagram

graph TD
    RPL27["RPL27"]
    neurodegeneration["neurodegeneration"]
    RPL27 -->|"implicated_in"| neurodegeneration
    style RPL27 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

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No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

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Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

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Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning RPL27 in their description or question text

No additional research found