Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about RPL38: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | RPL38 |
| Function | encodes a ribosomal protein component of the 60S large ribosomal subunit. |
| Molecular Weight | 8 kDa |
| Amino Acids | 71 aa |
| Ensembl ID | ENSG00000120314 |
| GeneCards | RPL38 |
| Human Protein Atlas | RPL38 |
| Protein synthesis | Contributes to peptide bond formation at the peptidyl transferase center |
| Ribosome assembly | Essential for proper 60S subunit biogenesis |
| rRNA interaction | Interacts with 28S rRNA to stabilize the large subunit |
| Translation termination | Participates in the release factor binding site |
| Associated Diseases | neurodegeneration |
| Interactions | RPS28, RPL35, TARDBP, RPS10, RPS16, RPS27 |
| KG Connections | 7 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
RPL38["<b>RPL38</b>"]
Ms{"Ms"}
RPL38 -->|"regulates"| Ms
neurodegeneration["neurodegeneration"]
RPL38 -->|"implicated in"| neurodegeneration
RPS28["RPS28"]
RPS28 -->|"interacts with"| RPL38
RPL35["RPL35"]
RPL35 -->|"interacts with"| RPL38
TARDBP["TARDBP"]
TARDBP -->|"interacts with"| RPL38
RPS10["RPS10"]
RPS10 -->|"interacts with"| RPL38
RPS16["RPS16"]
RPS16 -->|"interacts with"| RPL38
RPS27["RPS27"]
RPS27 -->|"interacts with"| RPL38
style RPL38 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0| Target | Relation | Type | Str |
|---|---|---|---|
| Ms | regulates | disease | 0.65 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity