gene

RPS3

Entity Detail — Knowledge Graph Node

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This page aggregates everything SciDEX knows about RPS3: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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🧬 Gene Info

Gene Symbol	RPS3
Function	is a core component of the 40S ribosomal subunit, occupying a position crucial for the translation initiation process.
Primary Expression	all human tissues, reflecting its essential role in protein synthesis
Subcellular Localization	mitochondria and influence the intrinsic apoptosis pathway
Molecular Weight	26.7 kDa
Amino Acids	243 aa
Ensembl ID	ENSG00000131789
GeneCards	RPS3
Human Protein Atlas	RPS3
Brain	Highest expression in the cerebral cortex and hippocampus, regions particularly vulnerable to neurodegeneration
Bone marrow	Active hematopoiesis requires high rates of protein synthesis
Testis	Spermatogenesis involves rapid cell division and protein synthesis
Proliferating cells	Actively dividing cells show elevated RPS3 expression
Associated Diseases	neurodegeneration
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (3)

Knowledge base pages for this entity

Canonical Page

Pathway Diagram

graph TD
    RPS3["RPS3"]
    neurodegeneration["neurodegeneration"]
    RPS3 -->|"implicated_in"| neurodegeneration
    style RPS3 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

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Mentioning Analyses (0)

Scientific analyses that reference this entity

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Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
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Related Papers (0)

Scientific publications cited in analyses involving this entity

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Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning RPS3 in their description or question text

No additional research found