Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about RPS3A: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
Comprehensive overview of RPS3A (ribosomal protein S3a), a component of the 40S ribosomal subunit with roles in translation, DNA repair, and apoptosis, implicated in Diamond-Blackfan anemia and neurodegenerative diseases.
| Gene Symbol | RPS3A |
| Full Name | Ribosomal Protein S3a |
| Aliases | RPS3A, S3a |
| Chromosome | 19p13.3 |
| Function | is a member of the ribosomal protein S3 family and is highly conserved across eukaryotes. |
| Amino Acids | 271 aa |
| UniProt ID | P23368 |
| NCBI Gene ID | 6208 |
| Ensembl ID | ENSG00000144040 |
| OMIM | 603012 |
| GeneCards | RPS3A |
| Human Protein Atlas | RPS3A |
| Tissue | Expression Level |
| Bone marrow | Very High |
| Brain | High |
| Associated Diseases | neurodegeneration |
| Interactions | TREK1 |
| KG Connections | 3 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
Knowledge base pages for this entity
graph TD
RPS3A["RPS3A"]
SUMO(["SUMO"])
TREK1(["TREK1"])
MHV68["MHV68"]
neurodegeneration["neurodegeneration"]
RPS3A -->|"binds"| SUMO
RPS3A -->|"interacts with"| TREK1
MHV68 -->|"interacts with"| RPS3A
RPS3A -->|"implicated in"| neurodegeneration
style RPS3A fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#fff
style SUMO fill:#1a237e,stroke:#4fc3f7,stroke-width:2px,color:#fff
style TREK1 fill:#1a237e,stroke:#4fc3f7,stroke-width:2px,color:#fff
style MHV68 fill:#1a1a2e,stroke:#888,stroke-width:2px,color:#fff
style neurodegeneration fill:#1a1a2e,stroke:#888,stroke-width:2px,color:#fff| Source | Relation | Type | Str |
|---|---|---|---|
| MHV68 | interacts_with | entity | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||