gene

SCARA1

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about SCARA1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

0Connections

0Hypotheses

0Analyses

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0Incoming

0Experiments

0Debates

Summary

Page for SCARA1 (Scavenger Receptor Class A Member 1)

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🧬 Gene Info

Gene Symbol	SCARA1
Full Name	SCARA1 (Scavenger Receptor Class A Member 1)
Aliases	Scavenger Receptor Class A Member 1
Chromosome	8p23.1.
Protein Type	Gene
Function	SCARA1 functions as a scavenger receptor with multiple ligands and functions
Primary Expression	Primarily macrophages, also microglia in brain
Molecular Weight	49 kDa
Amino Acids	471 aa
Pathways	NF-κB
UniProt ID	Q9Y6Q9
NCBI Gene ID	4451
Ensembl ID	ENSG00000138206
GeneCards	SCARA1
Human Protein Atlas	SCARA1
Associated Diseases	neurodegeneration
Databases	GeneCards HPA STRING

🔮 Predicted Structure: SCARA1 — AlphaFold Q9Y6Q9 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (4)

Knowledge base pages for this entity

Canonical Page

Pathway Diagram

graph TD
    SCARA1["SCARA1"]
    Amyloid_Beta["Amyloid Beta"]
    Amyloid_Beta_Uptake["Amyloid Beta Uptake"]
    neurodegeneration["neurodegeneration"]

    SCARA1 -->|"binds"| Amyloid_Beta
    SCARA1 -->|"involved in"| Amyloid_Beta_Uptake
    SCARA1 -->|"implicated in"| neurodegeneration

    style SCARA1 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#fff
    style Amyloid_Beta fill:#1a1a2e,stroke:#888,stroke-width:2px,color:#fff
    style Amyloid_Beta_Uptake fill:#1a1a2e,stroke:#888,stroke-width:2px,color:#fff
    style neurodegeneration fill:#1a1a2e,stroke:#888,stroke-width:2px,color:#fff

Outgoing (0)

Target	Relation	Type	Str
No outgoing edges

Incoming (0)

Source	Relation	Type	Str
No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity