gene

SCN7A

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about SCN7A: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

Page for SCN7A Gene

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🧬 Gene Info

Gene Symbol	SCN7A
Full Name	Sodium Voltage-Gated Channel Alpha Subunit 7
Chromosome	2q21.1
Protein Type	Channel
Function	encodes an atypical sodium channel that was originally designated as a "sodium leak channel" due to its unique gating properties, though subsequent research established its voltage-gated nature[@ei...
Primary Expression	sensory neurons, astrocytes, and certain hypothalamic nuclei, where it participates in sodium sensing, me
Molecular Weight	220 kDa
Amino Acids	018 aa
Exons	24
Gene Type	Protein coding
UniProt ID	Q9UQD0
NCBI Gene ID	6332
Ensembl ID	ENSG00000136546
GeneCards	SCN7A
Human Protein Atlas	SCN7A
Associated Diseases	neurodegeneration
Databases	GeneCards HPA STRING

🔮 Predicted Structure: SCN7A — AlphaFold Q9UQD0 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (5)

Knowledge base pages for this entity

Canonical Page

Pathway Diagram

graph TD
    SCN7A["SCN7A"]
    neurodegeneration["neurodegeneration"]
    SCN7A -->|"implicated_in"| neurodegeneration
    style SCN7A fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

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No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

SCN7A

Understanding Entity Pages

Summary

Wiki Pages (5)

SCN7A Gene

Voltage-Gated Sodium (NaV) Channel Neurons

SCN7A Protein (Sodium Voltage-Gated Channel Alpha Subunit 7)

Proteins