gene

SLC22A6

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about SLC22A6: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

SLC22A6 — Solute Carrier Family 22 Member 6 (OAT1)

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🧬 Gene Info

Gene Symbol	SLC22A6
Full Name	Solute Carrier Family 22 Member 6 (Organic Anion Transporter 1)
Aliases	Solute Carrier Family 22 Member 6 (OAT1)
Chromosome	11q13
Protein Type	Transporter
Function	is a major urate transporter in the kidney.
Primary Expression	the kidney proximal tubules
Subcellular Localization	the basolateral membrane of tubular cells, where it interfaces with peritubular capillaries. Minor expression has been d
UniProt ID	O15259
NCBI Gene ID	6579
Ensembl ID	ENSG00000197905
OMIM	607482
GeneCards	SLC22A6
Human Protein Atlas	SLC22A6
Associated Diseases	neurodegeneration
Databases	GeneCards HPA STRING

🔮 Predicted Structure: SLC22A6 — AlphaFold O15259 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (3)

Knowledge base pages for this entity

Canonical Page

Pathway Diagram

graph TD
    SLC22A6["SLC22A6"]
    neurodegeneration["neurodegeneration"]
    SLC22A6 -->|"implicated_in"| neurodegeneration
    style SLC22A6 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity