gene

SLC30A5

Entity Detail — Knowledge Graph Node

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This page aggregates everything SciDEX knows about SLC30A5: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

Page for SLC30A5 — Solute Carrier Family 3 Member 0A5 (SLC30A5)

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🧬 Gene Info

Gene Symbol	SLC30A5
Full Name	Solute Carrier Family 30 Member 5 (SLC30A5)
Chromosome	3p21
Protein Type	Transporter
Function	is a member of the SLC30 family of zinc transporters that facilitates zinc efflux from the cytoplasm into intracellular compartments[@huang2013].
Primary Expression	various tissues including the brain, making it relevant to neurodegenerative disease research[@jackson2007]
Subcellular Localization	the Golgi apparatus and plasma membrane, where it plays a critical role in zinc sequestration and homeostasis[@nishida20
Amino Acids	638 aa
Exons	13
UniProt ID	Q8TAP9
NCBI Gene ID	7783
Ensembl ID	ENSG00000146039
OMIM	607339
GeneCards	SLC30A5
Human Protein Atlas	SLC30A5
Associated Diseases	neurodegeneration
Databases	GeneCards HPA STRING

🔮 Predicted Structure: SLC30A5 — AlphaFold Q8TAP9 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

SLC30A5 — Solute Carrier Family 3 Member 0A5 (SLC30A5)

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Pathway Diagram

flowchart TD
    A["Upstream Regulators"] --> B["SLC30A5"]
    B --> C["Molecular Mechanism"]
    C --> D["Cellular Effects"]
    D --> E["Pathological Consequences"]

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

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Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
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