gene

SLC3A1

Entity Detail — Knowledge Graph Node

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This page aggregates everything SciDEX knows about SLC3A1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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🧬 Gene Info

Gene Symbol	SLC3A1
Full Name	Solute Carrier Family 3 Member 1
Chromosome	2p16.3
Function	Essential amino acid transport:
Primary Expression	the kidney and intestinal epithelium where it mediates reabsorption of cystine and dibasic amino acids [@palacin2005]
Subcellular Localization	- Proximal renal tubule: Apical membrane of S1-S2 segments
Molecular Weight	79 kDa
Amino Acids	683 aa
Exons	8
UniProt ID	Q07817
NCBI Gene ID	10251
Ensembl ID	ENSG00000166391
GeneCards	SLC3A1
Human Protein Atlas	SLC3A1
Single transmembrane helix (aa 481-503)	Anchors the protein in the plasma membrane
Associated Diseases	neurodegeneration
Databases	GeneCards HPA STRING

🔮 Predicted Structure: SLC3A1 — AlphaFold Q07817 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

SLC3A1 — Solute Carrier Family 3 Member 1

gene · 1345 words

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Pathway Diagram

graph TD
    SLC3A1["SLC3A1"]
    neurodegeneration["neurodegeneration"]
    SLC3A1 -->|"implicated_in"| neurodegeneration
    style SLC3A1 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

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No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

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Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
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Related Papers (0)

Scientific publications cited in analyses involving this entity

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Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning SLC3A1 in their description or question text

No additional research found