gene 1,345 words KG: SLC3A1
Contents

SLC3A1 — Solute Carrier Family 3 Member 1

🧬 Gene Info
Gene SymbolSLC3A1
Full NameSolute Carrier Family 3 Member 1
Chromosome2p16.3
FunctionEssential amino acid transport:
Primary Expressionthe kidney and intestinal epithelium where it mediates reabsorption of cystine and dibasic amino acids [@palacin2005]
Subcellular Localization- **Proximal renal tubule**: Apical membrane of S1-S2 segments
Molecular Weight79 kDa
Amino Acids683 aa
Exons8
UniProt IDQ07817
NCBI Gene ID10251
Ensembl IDENSG00000166391
GeneCardsSLC3A1
Human Protein AtlasSLC3A1
TransporterGene
Associated Diseasesneurodegeneration
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (4)

SASP-Mediated Complement Cascade Amplification
Score: 0.70
Magnetosonic-Triggered Transferrin Receptor Clustering
Score: 0.47
Pericyte Contractility Reset via Selective PDGFR-β Agonism
Score: 0.44
Bacterial Enzyme-Mediated Dopamine Precursor Synthesis
Score: 0.36

Related Analyses (4)

Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived
Perivascular spaces and glymphatic clearance failure in AD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (12)

Proposed experiment from debate on Synaptic pruning by micro
falsification · proposed · Score: 0.40
Proposed experiment from debate on Senolytics targeting p16/
falsification · proposed · Score: 0.40
Mechanism: Why Does Amyloid Removal Only Slow Decline 27%?
clinical · proposed · Score: 0.40
Experiment: Autoimmune Hypothesis Testing in AD
clinical · proposed · Score: 0.40
Mixed Pathology Effects on Parkinson's Disease Progression a
clinical · proposed · Score: 0.40

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in