protein

SLIT1PROTEIN

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about SLIT1PROTEIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

0Connections

0Hypotheses

0Analyses

0Outgoing

0Incoming

0Experiments

0Debates

Summary

Slit 1 Protein is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.

View on Wiki →

No AI portrait yet

🔬 Protein Info

Gene Symbol	SLIT1PROTEIN
Full Name	Slit homolog 1 protein
Protein Family	Slit family (SLIT1-3)
Function	is an important component in the neurobiology of neurodegenerative diseases.
Primary Expression	the midline raphe and acts as a chemorepulsive cue for commissural axons:
Subcellular Localization	</td><td>Extracellular matrix, growth cones, plasma membrane</td></tr>
Molecular Weight	~170 kDa (full-length); ~140 kDa (processed)
UniProt ID	Q9MQZ3
GeneCards	SLIT1PROTEIN
Human Protein Atlas	SLIT1PROTEIN
Midline avoidance	Slit1-Robo signaling prevents axons from crossing the midline, ensuring proper formation of bilateral neural circuits
Corticospinal tract	Slit1 guides corticospinal motor neurons to their correct targets
Olfactory system	Slit1 mediates the organization of olfactory bulb interneurons
Cortical interneurons	Guides GABAergic interneurons from the medial ganglionic eminence to the cortex
GnRH neurons	Influences the migration of gonadotropin-releasing hormone neurons
Associated Diseases	neurodegeneration
Databases	GeneCards NCBI Gene HPA STRING

🔮 Predicted Structure: SLIT1PROTEIN — AlphaFold Q9MQZ3 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

Slit 1 Protein

protein · 1051 words

→

Pathway Diagram

graph TD
    SLIT1PROTEIN["SLIT1PROTEIN"]
    neurodegeneration["neurodegeneration"]
    SLIT1PROTEIN -->|"implicated_in"| neurodegeneration
    style SLIT1PROTEIN fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

Target	Relation	Type	Str
No outgoing edges

Incoming (0)

Source	Relation	Type	Str
No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning SLIT1PROTEIN in their description or question text

No additional research found