SORT1

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolSORT1
Namesortilin 1
Typeprotein-coding
Sourcemygene

Summary

This gene encodes a member of the VPS10-related sortilin family of proteins. The encoded preproprotein is proteolytically processed by furin to generate the mature receptor. This receptor plays a role in the trafficking of different proteins to either the cell surface, or subcellular compartments such as lysosomes and endosomes. Expression levels of this gene may influence the risk of myocardial infarction in human patients. Alternative splicing results in multiple transcript variants. [provided

22Connections

This is an externally resolved entity

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