gene 859 words KG: SORT1
Contents

SORT1 Gene

🧬 Gene Info
Gene SymbolSORT1
Full NameSortilin 1
Chromosome1p13
Protein TypeReceptor
Functionis an important component in the neurobiology of neurodegenerative diseases.
Primary Expressionthe central nervous system:
Subcellular Localizationthe trans-Golgi network
Molecular Weight110 kDa
PathwaysMAPK, PI3K pathway
UniProt IDQ99549
NCBI Gene ID602458
Ensembl IDENSG00000134247
OMIM602458
GeneCardsSORT1
Human Protein AtlasSORT1
Associated DiseasesAlzheimer
InteractionsENDOSOMES, IGF2R, LRP1, NEK7, RAB7A
KG Connections23 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Knowledge Graph (12 edges)

ATP1A1 regulates SORT1
RAB11B regulates SORT1
AMBRA1 regulates SORT1
APOE associated_with SORT1
RAB7A interacts_with SORT1
IGF2R interacts_with SORT1
SORT1 interacts_with NEK7
SORT1 associated_with APOE
SORT1 biomarker_for TREM2
SORT1 biomarker_for neuroinflammation

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