protein

SYNJ2PROTEIN

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about SYNJ2PROTEIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

Synaptojanin 2 Protein is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.

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🔬 Protein Info

Gene Symbol	SYNJ2PROTEIN
Protein Type	Phosphatase
Function	is an important component in the neurobiology of neurodegenerative diseases.
Subcellular Localization	- SYNJ2b: Broader expression including immune cells and cancer cells ## Mol
Molecular Weight	175 kDa
GeneCards	SYNJ2PROTEIN
Human Protein Atlas	SYNJ2PROTEIN
C2 domains	Calcium-dependent membrane association
SYNJ2a	Neuron-specific isoform with presynaptic localization
SYNJ2b	Broader expression including immune cells and cancer cells
AMPA Receptor Endocytosis	Controls synaptic strength through receptor trafficking
Dendritic Spine Morphogenesis	Regulates spine development and maintenance
Long-term Depression (LTD)	Mediates activity-dependent synaptic weakening
Associated Diseases	neurodegeneration
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

Synaptojanin 2 Protein

protein · 936 words

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Pathway Diagram

graph TD
    SYNJ2PROTEIN["SYNJ2PROTEIN"]
    neurodegeneration["neurodegeneration"]
    SYNJ2PROTEIN -->|"implicated_in"| neurodegeneration
    style SYNJ2PROTEIN fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

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No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

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Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

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Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning SYNJ2PROTEIN in their description or question text

No additional research found