Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about SAVI: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | SAVI |
| Key Genes/Proteins | STING1, AUTOANTIBODIES |
| Related Diseases | VASCULOPATHY, ILD, T_CELL_DEFICIENCY |
Knowledge base pages for this entity
graph TD
SAVI["SAVI"]
SAVI -->|"downregulates"| Memory_CD8__Cells["Memory CD8+ Cells"]
SAVI -.biomarker for.-> Rheumatoid_Factor["Rheumatoid Factor"]
SAVI -->|"causes"| VASCULOPATHY["VASCULOPATHY"]
SAVI -->|"causes"| ILD["ILD"]
SAVI -->|"causes"| T_CELL_DEFICIENCY["T_CELL_DEFICIENCY"]
STING1["STING1"] -->|"causes"| SAVI
Ruxolitinib["Ruxolitinib"] -->|"treats"| SAVI| Target | Relation | Type | Str |
|---|---|---|---|
| VASCULOPATHY | causes | phenotype | 0.72 |
| ILD | causes | disease | 0.72 |
| AUTOANTIBODIES | associated_with | protein | 0.56 |
| T_CELL_DEFICIENCY | causes | phenotype | 0.56 |
| Source | Relation | Type | Str |
|---|---|---|---|
| STING1 | causes | gene | 0.72 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||