gene

TAOK1

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about TAOK1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

6Connections

0Hypotheses

0Analyses

4Outgoing

2Incoming

0Experiments

0Debates

Summary

TAO1 kinase

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🧬 Gene Info

Gene Symbol	TAOK1
Chromosome	17p11.2
Protein Family	MAP3K (Ste11) family, TAOK subfamily
Protein Type	Kinase
Function	p38 MAPK Activation: Phosphorylates and activates MKK3/MKK6, which in turn activate p38α/β
Molecular Weight	122 kDa
Exons	21
Pathways	MAPK pathway, MAPK
UniProt ID	Q9UL54
GeneCards	TAOK1
Human Protein Atlas	TAOK1
Associated Diseases	neurodegeneration
KG Connections	6 knowledge graph edges
Databases	GeneCards NCBI Gene HPA STRING

🔮 Predicted Structure: TAOK1 — AlphaFold Q9UL54 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

TAOK1 Gene

gene · 957 words

→

TAOK1 Protein

protein · 705 words

→

Pathway Diagram

graph TD
    TAOK1["TAOK1"]
    Als["Als"]
    TAOK1 -->|"contributes_to"| Als
    Ms["Ms"]
    TAOK1 -->|"regulates"| Ms
    neurodegeneration["neurodegeneration"]
    TAOK1 -->|"implicated in"| neurodegeneration
    style TAOK1 fill:#1a237e,stroke:#4fc3f7,color:#4fc3f7

Outgoing (4)

Target	Relation	Type	Str
benchmark_ot_ad_answer_key:TAOK1	data_in	dataset_row	0.00
ds-83b31ef18d49	provides_data_for	dataset	1.00
Als	contributes_to	disease	0.65
Ms	regulates	disease	0.65

Incoming (2)

Source	Relation	Type	Str
benchmark_ot_ad_answer_key:TAOK1	data_in	dataset_row	0.00
ds-83b31ef18d49	data_in	dataset	1.00

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning TAOK1 in their description or question text

No additional research found