gene

TAOK2

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about TAOK2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

1Connections

0Hypotheses

0Analyses

0Outgoing

1Incoming

Summary

TAO2 kinase

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🧬 Gene Info

Gene Symbol	TAOK2
Chromosome	16p11.2
Protein Family	MAP3K (Ste11) family, TAOK subfamily
Protein Type	Kinase
Function	p38 MAPK Activation: Phosphorylates and activates MKK3/MKK6 upstream of p38
Molecular Weight	125 kDa
Exons	22
Pathways	MAPK, MAPK pathway
UniProt ID	Q9Y2M8
GeneCards	TAOK2
Human Protein Atlas	TAOK2
Official Full Name	Thousand and One Amino Acid Kinase 2
Previous Symbols	TAO2, MAP3K17
Exon Count	22 exons
Compound	Mechanism
Associated Diseases	neurodegeneration
Interactions	EEF2
KG Connections	1 knowledge graph edges
Databases	GeneCards NCBI Gene HPA STRING

🔮 Predicted Structure: TAOK2 — AlphaFold Q9Y2M8 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (6)

Knowledge base pages for this entity

Canonical Page

Pathway Diagram

flowchart TD
    N0["TAOK2"]
    N1["EEF2"]
    N1 -->|"phosphorylates"| N0
    N2["neurodegeneration"]
    N0 -->|"implicated in"| N2

    classDef gene fill:#1a3a2a,stroke:#4caf50,color:#e0e0e0
    classDef protein fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
    classDef disease fill:#3a1a1a,stroke:#ef5350,color:#e0e0e0
    classDef pathway fill:#2a1a3a,stroke:#ce93d8,color:#e0e0e0
    classDef mechanism fill:#2a2a1a,stroke:#ffd54f,color:#e0e0e0
    class N1 gene

Outgoing (0)

Target	Relation	Type	Str
No outgoing edges

Incoming (1)

Source	Relation	Type	Str
EEF2	phosphorylates	gene	0.90

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

TAOK2

Understanding Entity Pages

Summary

Wiki Pages (6)

TAOK2 Gene

Eukaryotic Translation Elongation Factor 2 (EEF2)

TAOK1 Protein

TAOK2 Protein