gene

TECPR2

Entity Detail — Knowledge Graph Node

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This page aggregates everything SciDEX knows about TECPR2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

Tectonin Beta-Propeller Repeat Containing 2

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🧬 Gene Info

Gene Symbol	TECPR2
Full Name	Tectonin Beta-Propeller Repeat Containing 2
Chromosome	14q31.3
Protein Type	Receptor
Function	It plays critical roles in ciliary signaling, neuronal migration, and synaptic function.
Primary Expression	regions affected in Parkinson disease
UniProt ID	Q9Y5P9
NCBI Gene ID	1615
Ensembl ID	ENSG00000167962
OMIM	615730
GeneCards	TECPR2
Human Protein Atlas	TECPR2
AHI1	Expressed in fetal and adult brain, with highest expression in cerebellum, basal ganglia, and hippocampus. Also expressed in kidney and testis. 6
GAD1	Broad expression in GABAergic neurons throughout the brain, including cortex, hippocampus, basal ganglia, and cerebellum. More abundant than GAD2 in most brain regions. 7
GAD2	Expressed in GABAergic neurons with synaptic localization. Higher expression in hippocampus and cerebellum compared to GAD1 in some regions. 8
Associated Diseases	neurodegeneration
Databases	GeneCards HPA STRING

🔮 Predicted Structure: TECPR2 — AlphaFold Q9Y5P9 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

Tectonin Beta-Propeller Repeat Containing 2

gene · 943 words

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Pathway Diagram

graph TD
    TECPR2["TECPR2"]
    neurodegeneration["neurodegeneration"]
    TECPR2 -->|"implicated_in"| neurodegeneration
    style TECPR2 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

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Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
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Related Papers (0)

Scientific publications cited in analyses involving this entity

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Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning TECPR2 in their description or question text

No additional research found