Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about TEX: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
Knowledge base pages for this entity
| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| Closed-loop tACS targeting entorhinal cortex layer II SST in | 0.625 | Alzheimer's disease | Circuit-level neural dynamics in neurode |
| Context-Dependent Cx43 Modulation Based on Disease Stage | 0.579 | cell biology | What is the relative contribution of con |
| Context-Dependent CRISPR Activation in Specific Neuronal Sub | 0.509 | neurodegeneration | CRISPR-based therapeutic approaches for |
Scientific analyses that reference this entity
neurodegeneration | 2026-04-15 | 2 hypotheses Top: 0.455
neurodegeneration | 2026-04-14 | 1 hypotheses Top: 0.606
neurodegeneration | 2026-04-13 | 2 hypotheses Top: 0.444
neurodegeneration | 2026-04-11 | 0 hypotheses
neurodegeneration | 2026-04-07 | 0 hypotheses
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| Autophagy and ALS: mechanistic insights and therapeutic implications. [PMID:34057020] | Chua JP, De Calbiac H, Kabashi E, Barmad | Autophagy | 2022 | 2 |
| Exploring Parkinson's through the Lens of Genomics and Bioinformatics. [PMID:39929729] | Menon V | Cold Spring Harb Perspect Med | 2026 | 0 |
| A Simple Method for RNA-Seq of Manually Isolated Chromatophores in Oryzias Fishe [PMID:41805030] | Goda M, Miyagi A, Sugiwaka K, Watanabe M | Dev Growth Differ | 2026 | 0 |
| Phosphate starvation induces root cell-type-specific transcriptional responses a [PMID:41952296] | González-García MP, Lanza M, Baca-Gonzál | New Phytol | 2026 | 0 |
| Cell-type resolved protein atlas of brain lysosomes identifies SLC45A1-associate [PMID:41576950] | ["Ghoochani A", "Heiby J", "Rawat E", "M | Cell | 2026 | 0 |
| Decoding Alzheimer's genetic risk through intercellular communication in the hum [PMID:41707523] | Lish AM, Young-Pearse TL | Current opinion in neurobiolog | 2026 | 0 |
| Neuromodulatory role and therapeutic potential of N 6 -methyladenosine RNA methy [PMID:40618260] | Zhang J, Ma W, Liu R, Li X, Yuan Z, Chen | Neural regeneration research | 2026 | 0 |
| Single-Cell Atlas of Transcription and Chromatin States Reveals Regulatory Progr [PMID:41676679] | Xie Y, Chang L, Zhong G, Rink JA, Báez-B | bioRxiv : the preprint server | 2026 | 0 |
| Metabolic rewiring prevents neurodegeneration caused by chronic mitochondrial dy [PMID:41151583] | Richhariya S, Shin D, Schlichting M, Ros | Current biology : CB | 2025 | 0 |
| Focused ultrasound widely broadens AAV-delivered Cas9 distribution and activity. [PMID:39893321] | Gumusgoz E, Kasiri S, Youssef I, Verma M | Gene therapy | 2025 | 0 |
| Connexin 43 drives glioblastoma cancer stem cell phenotypes through a WNK lysine [PMID:40946315] | Mulkearns-Hubert EE, Hajdari N, Hong ES, | Cell Rep | 2025 | 0 |
| Integrative analysis of gene expression and histone modifications for DES, DSP, [PMID:41275133] | Saeed S, Hoffmann A, Svensson SIA, Visno | Mol Med | 2025 | 0 |
| Anterior cingulate cortex parvalbumin and somatostatin interneurons shape social [PMID:40320404] | Qi C, Sima W, Mao H, Hu E, Ge J et al. | Nat Commun | 2025 | 0 |
| Distinct dendritic integration strategies control dynamics of inhibition in the [PMID:40592329] | Morabito A, Zerlaut Y, Dhanasobhon D, Be | Neuron | 2025 | 0 |
| Cell-Type Resolved Protein Atlas of Brain Lysosomes Identifies SLC45A1-Associate [PMID:39464040] | ["Ghoochani A", "Heiby J", "Rawat E", "M | bioRxiv : the preprint server | 2024 | 0 |
| Cortical somatostatin long-range projection neurons and interneurons exhibit div [PMID:38086373] | Fisher J, Verhagen M, Long Z, Moissidis | Neuron | 2024 | 0 |
| Locus Coeruleus-Dorsolateral Septum Projections Modulate Depression-Like Behavio [PMID:38155473] | Zhang Q, Xue Y, Wei K, Wang H, Ma Y et a | Adv Sci (Weinh) | 2024 | 0 |
| Somatostatin and the pathophysiology of Alzheimer's disease. [PMID:38484981] | Almeida VN | Ageing Res Rev | 2024 | 0 |
| Somatostatin interneurons control the timing of developmental desynchronization [PMID:38599213] | Mòdol L, Moissidis M, Selten M, Oozeer F | Neuron | 2024 | 0 |
| De novo gene synthesis by an antiviral reverse transcriptase. [PMID:39116258] | Tang S, Conte V, Zhang DJ, Žedaveinytė R | Science | 2024 | 0 |