concept

ETV6

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about ETV6: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

73Connections

0Hypotheses

0Analyses

47Outgoing

26Incoming

Summary

ETV6 is a concept in neurodegeneration research. Key relationships include: activates, expressed in, associated with. Associated with ALS, Als, Breast Cancer. Connected to 63 entities in the SciDEX knowledge graph.

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💡 Concept Info

Name	ETV6
Key Genes/Proteins	CANCER, CAMK4
Related Diseases	Cancer, Tumor, Leukemia, Als, Ms

Pathway Diagram

graph TD
    ETV6["<b>ETV6</b>"]
    ETV6 -->|"activates"| Leukemia["Leukemia"]
    ETV6 -->|"activates"| Als["Als"]
    ETV6 -->|"target for"| Cancer["Cancer"]
    ETV6 -->|"target for"| Tumor["Tumor"]
    ETV6 -->|"activates"| ALS["ALS"]
    ETV6 -->|"activates"| CAMK4["CAMK4"]
    ETV6 -->|"expressed in"| NTRK3["NTRK3"]
    ETV6 -->|"expressed in"| CSF1R["CSF1R"]
    ETV6 -->|"activates"| GENES["GENES"]
    ETV6 -->|"activates"| ZBTB20["ZBTB20"]
    ANK3["ANK3"] -->|"activates"| ETV6
    ZBTB20 -->|"activates"| ETV6
    TYK2["TYK2"] -->|"activates"| ETV6
    PTK2B["PTK2B"] -->|"activates"| ETV6
    IL7R["IL7R"] -->|"activates"| ETV6
    JAK2["JAK2"] -->|"expressed in"| ETV6
    PDGFRB["PDGFRB"] -->|"expressed in"| ETV6
    ABL2["ABL2"] -->|"expressed in"| ETV6
    NTRK3 -->|"expressed in"| ETV6
    BCL_2["BCL-2"] -->|"target for"| ETV6
    CAMK4 -->|"activates"| ETV6
    CD8["CD8"] -->|"target for"| ETV6

Outgoing (47)

Target	Relation	Type	Str
Cancer	associated_with	disease	0.75
CANCER	associated_with	gene	0.70
Tumor	associated_with	disease	0.65
Leukemia	activates	disease	0.65
Als	activates	disease	0.65
Leukemia	therapeutic_target	disease	0.65
Als	therapeutic_target	disease	0.65
Cancer	therapeutic_target	disease	0.65
Tumor	therapeutic_target	disease	0.65
Ms	associated_with	disease	0.65
Carcinoma	associated_with	disease	0.65
ALS	activates	disease	0.65
Breast Cancer	associated_with	disease	0.65
Carcinoma	causes	disease	0.65
CAMK4	activates	gene	0.60
NTRK3	expressed_in	gene	0.60
CSF1R	expressed_in	gene	0.60
GENES	activates	gene	0.60
ZBTB20	activates	gene	0.60
CD8	associated_with	gene	0.60
ANK3	activates	gene	0.60
SPP1	associated_with	gene	0.60
ABL1	expressed_in	gene	0.60
PDGFRB	expressed_in	gene	0.60
JAK2	expressed_in	gene	0.60
EPOR	expressed_in	gene	0.60
TYK2	activates	gene	0.60
IL7R	activates	gene	0.60
KMT2A	therapeutic_target	gene	0.60
RUNX1	activates	gene	0.60
SPP1	therapeutic_target	gene	0.60
BCL-2	therapeutic_target	gene	0.60
PTK2B	activates	gene	0.60
TSLP	activates	gene	0.60
ABL2	expressed_in	gene	0.60
NTRK3	causes	gene	0.60
CDH1	causes	gene	0.60
GENES	associated_with	gene	0.60
RNA	associated_with	gene	0.60
AND	activates	gene	0.60
AND	expressed_in	gene	0.60
FLT3	activates	gene	0.60
CRLF2	activates	gene	0.60
T Cell	associated_with	cell_type	0.60
TEX	expressed_in	cell_type	0.56
T Cell	expressed_in	cell_type	0.55
B Cell	expressed_in	cell_type	0.55

Incoming (26)

Source	Relation	Type	Str
SPP1	associated_with	gene	0.60
CD8	associated_with	gene	0.60
ANK3	activates	gene	0.60
ZBTB20	activates	gene	0.60
TYK2	activates	gene	0.60
PTK2B	activates	gene	0.60
IL7R	activates	gene	0.60
JAK2	expressed_in	gene	0.60
PDGFRB	expressed_in	gene	0.60
ABL2	expressed_in	gene	0.60
NTRK3	expressed_in	gene	0.60
BCL-2	therapeutic_target	gene	0.60
CAMK4	activates	gene	0.60
CD8	therapeutic_target	gene	0.60
ABL1	expressed_in	gene	0.60
NTRK3	associated_with	gene	0.60
CANCER	associated_with	gene	0.60
CDH1	associated_with	gene	0.60
GENES	activates	gene	0.60
CSF1R	expressed_in	gene	0.60
EPOR	expressed_in	gene	0.60
TSLP	activates	gene	0.60
FLT3	activates	gene	0.60
CRLF2	activates	gene	0.60
RNA	associated_with	gene	0.60
dasatinib	targets	drug	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found