Entity Detail โ Knowledge Graph Node
This page aggregates everything SciDEX knows about TOMM40L: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
| Gene Symbol | TOMM40L |
| Full Name | Translocase of Outer Mitochondrial Membrane 40 Like |
| Chromosome | 1q21.3 |
| Function | This process is critical for mitochondrial biogenesis and function: |
| Molecular Weight | 43 kDa |
| Amino Acids | 384 aa |
| Exons | 9 |
| Ensembl ID | ENSG00000146215 |
| GeneCards | TOMM40L |
| Human Protein Atlas | TOMM40L |
| TOMM20 | Receptor protein that recognizes mitochondrial targeting signals |
| TOMM22 | Central receptor component |
| TOMM40 | Channel-forming subunit (TOMM40L is a paralog) |
| TOMM5 | Small accessory subunit |
| TOMM7 | Accessory subunit for complex stability |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
TOMM40L["TOMM40L"]
neurodegeneration["neurodegeneration"]
TOMM40L -->|"implicated_in"| neurodegeneration
style TOMM40L fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||