protein

UBC9

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about UBC9: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

1Connections
0Hypotheses
0Analyses
0Outgoing
1Incoming

No summary available yet. View on Wiki →

🔬 Protein Info
Gene SymbolUBC9
FunctionUBC9 is the sole E2 conjugating enzyme for SUMO (Small Ubiquitin-like Modifier) conjugation. It has a characteristic UBC9 fold consisting of a four-helix bundle structure that facilitates binding t...
Subcellular Localizationand export signals for shuttling ## Normal Function in the Nervous System UBC9
GeneCardsUBC9
Human Protein AtlasUBC9
InteractionsRANBP2
KG Connections1 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Wiki Pages (18)

Knowledge base pages for this entity

cbs-psp-daily-action-plan

therapeutic · 30834 words

Protein SUMOylation Pathway in Neurodegeneration

mechanism · 3042 words

Tau Post-Translational Modifications in 4R-Tauopathies

mechanism · 2594 words

UBE2I Protein

protein · 2467 words

UBE2I — SUMO-Conjugating Enzyme

gene · 2037 words

Pathway Diagram

flowchart TD
    N0["UBC9"]
    N1["RANBP2"]
    N1 -->|"interacts with"| N0
    N2["RANGAP1"]
    N0 -->|"interacts with"| N2

    classDef gene fill:#1a3a2a,stroke:#4caf50,color:#e0e0e0
    classDef protein fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
    classDef disease fill:#3a1a1a,stroke:#ef5350,color:#e0e0e0
    classDef pathway fill:#2a1a3a,stroke:#ce93d8,color:#e0e0e0
    classDef mechanism fill:#2a2a1a,stroke:#ffd54f,color:#e0e0e0
    class N1 protein
    class N2 protein

Outgoing (0)

TargetRelationTypeStr
No outgoing edges

Incoming (1)

SourceRelationTypeStr
RANBP2interacts_withprotein0.95

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found