gene

UBXD2

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about UBXD2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

0Connections

0Hypotheses

0Analyses

0Outgoing

0Incoming

0Experiments

0Debates

No summary available yet.

View on Wiki →

No AI portrait yet

🧬 Gene Info

Gene Symbol	UBXD2
Full Name	UBX domain containing 2
Chromosome	9q34.3
Function	ERAD adaptor, VCP/p97 regulator
Primary Expression	most human tissues, with highest expression in brain, heart, and skeletal muscle
Subcellular Localization	aggresomes, which are aggregates of misfolded proteins, suggesting a role in aggregate clearance[@chitnus2021]
Amino Acids	350 aa
Exons	6
UniProt ID	Q9Y5X5
NCBI Gene ID	10277
Ensembl ID	ENSG00000130244
GeneCards	UBXD2
Human Protein Atlas	UBXD2
Aggresome Targeting	UBXD2 can localize to aggresomes, which are aggregates of misfolded proteins, suggesting a role in aggregate clearance[@chitnus2021]
Autophagy Regulation	The protein interacts with autophagy receptors and may contribute to selective autophagy pathways[@gao2023]
Associated Diseases	neurodegeneration
Databases	GeneCards HPA STRING

🔮 Predicted Structure: UBXD2 — AlphaFold Q9Y5X5 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

UBXD2 (UBXN6) — UBX Domain Containing 2

gene · 1531 words

→

Pathway Diagram

graph TD
    UBXD2["UBXD2"]
    neurodegeneration["neurodegeneration"]
    UBXD2 -->|"implicated_in"| neurodegeneration
    style UBXD2 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

Target	Relation	Type	Str
No outgoing edges

Incoming (0)

Source	Relation	Type	Str
No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning UBXD2 in their description or question text

No additional research found