Entity Detail โ Knowledge Graph Node
This page aggregates everything SciDEX knows about UBXD5: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | UBXD5 |
| Full Name | UBX domain containing 5 |
| Chromosome | 19q13.42 |
| Function | ERAD adaptor, VCP/p97 regulator, aggresome targeting |
| Primary Expression | both excitatory and inhibitory neurons, as well as in glial cells including astrocytes and microglia |
| Subcellular Localization | aggresomes, which are microtubule-organizing centers for protein aggregate sequestration[@yang2019] |
| Amino Acids | 80 aa |
| UniProt ID | Q9NVA1 |
| NCBI Gene ID | 58515 |
| Ensembl ID | ENSG00000130413 |
| GeneCards | UBXD5 |
| Human Protein Atlas | UBXD5 |
| Protein Length | ~380 aa |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsHPASTRING |
Knowledge base pages for this entity
graph TD
UBXD5["UBXD5"]
neurodegeneration["neurodegeneration"]
UBXD5 -->|"implicated_in"| neurodegeneration
style UBXD5 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
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| No outgoing edges | |||
| Source | Relation | Type | Str |
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| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
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| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
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| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity