gene

VASP

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about VASP: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

1Connections

0Hypotheses

1Analyses

0Outgoing

1Incoming

0Experiments

1Debates

Summary

Page for VASP (Vasodilator-Stimulated Phosphoprotein)

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🧬 Gene Info

Gene Symbol	VASP
Full Name	Vasodilator-Stimulated Phosphoprotein
Chromosome	19q13.2
Function	VASP (Vasodilator-Stimulated Phosphoprotein) is an actin-binding protein that regulates actin dynamics, cell adhesion, and cell migration.
Primary Expression	the nervous system:
UniProt ID	[P50552](https://www.uniprot.org/uniprot/P50552)
Ensembl ID	ENSG00000125753
GeneCards	VASP
Human Protein Atlas	VASP
Ena/VASP Family Proteins	Mena, EVL
Interaction Partners	Profilin, FAK, Arp2/3 complex
Signaling Pathways	cAMP/PKA, cGMP/PKG cascades
Associated Diseases	neurodegeneration
KG Connections	1 knowledge graph edges
Databases	GeneCards NCBI Gene HPA STRING

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

VASP (Vasodilator-Stimulated Phosphoprotein)

gene · 595 words

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Pathway Diagram

graph TD
    VASP["VASP"]
    neurodegeneration["neurodegeneration"]
    VASP -->|"implicated_in"| neurodegeneration
    style VASP fill:#006494,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0
    style neurodegeneration fill:#455a64,stroke:#333,stroke-width:1px,color:#e0e0e0

Outgoing (0)

Target	Relation	Type	Str
No outgoing edges

Incoming (1)

Source	Relation	Type	Str
TRIM9	regulates	protein	0.70

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (1)

Scientific analyses that reference this entity

Do astrocytes functionally express TRIM46, and can PKCα phosphorylate it to driv

molecular biology | 2026-04-13 | 0 hypotheses

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (1)

Multi-agent debates referencing this entity

The P2X7 hypothesis relies on TRIM46-mediated actin polymerization in astrocytes

closed · Rounds: 4 · Score: 0.95 · 2026-04-16

Related Research

Hypotheses and analyses mentioning VASP in their description or question text

No additional research found