Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about VRK1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
| Gene Symbol | VRK1 |
| Full Name | Vaccinia-Related Kinase 1 |
| Chromosome | 14q32.33 |
| Protein Type | Kinase |
| Function | VRK1 encodes a serine/threonine protein kinase belonging to the VRK (Vaccinia-Related Kinase) family. |
| UniProt ID | Q15818 |
| NCBI Gene ID | 7443 |
| Ensembl ID | ENSG00000100749 |
| OMIM | 604680 |
| GeneCards | VRK1 |
| Human Protein Atlas | VRK1 |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsHPASTRING |
Knowledge base pages for this entity
graph TD
VRK1["VRK1"]
neurodegeneration["neurodegeneration"]
VRK1 -->|"implicated_in"| neurodegeneration
style VRK1 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity