Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about ZO-1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Target | Relation | Type | Str |
|---|---|---|---|
| benchmark_ot_ad_answer_key:ZO-1 | data_in | dataset_row | 0.00 |
| h-013cc31a80 | targeted_by | hypothesis | 1.00 |
| Blood-Brain Barrier Integrity | involved_in | process | 0.80 |
| Source | Relation | Type | Str |
|---|---|---|---|
| benchmark_ot_ad_answer_key:ZO-1 | data_in | dataset_row | 0.00 |
| h-013cc31a80 | targets | hypothesis | 1.00 |
| Litebamine | upregulates | compound | 0.90 |
| Betulinic Acid | upregulates | compound | 0.85 |
| CSD | activates | drug | 0.80 |
| SLC26A3 | regulates | gene | 0.80 |
| L. reuteri-CMVs | activates | drug | 0.80 |
| propionate | activates | drug | 0.80 |
| MMP-9 | degrades | protein | 0.70 |
| MLCK | regulates | gene | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
neurodegeneration | 2026-04-26 | 8 hypotheses Top: 0.745
neurodegeneration | 2026-04-16 | 14 hypotheses Top: 0.806
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
closed · Rounds: 4 · Score: 1.00 · 2026-04-26
closed · Rounds: 4 · Score: 0.76 · 2026-04-23
closed · Rounds: 7 · Score: 0.87 · 2026-04-16
Hypotheses and analyses mentioning ZO-1 in their description or question text
No additional research found