Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about als-genetic-variants: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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Knowledge base pages for this entity
graph TD
als_genetic_variants["als-genetic-variants"]
CUL2["CUL2"]
als_genetic_variants -->|"inhibits"| CUL2
DES["DES"]
als_genetic_variants -->|"associated_with"| DES
NOS2["NOS2"]
als_genetic_variants -->|"protects_against"| NOS2
KCNJ6["KCNJ6"]
als_genetic_variants -->|"expressed_in"| KCNJ6
ALS["ALS"]
als_genetic_variants -->|"modulates"| ALS
ICAM1["ICAM1"]
als_genetic_variants -->|"activates"| ICAM1
als_genetic_variants -->|"phosphorylates"| ALS
als_genetic_variants -->|"biomarker_for"| ALS
HDAC3["HDAC3"]
als_genetic_variants -->|"associated_with"| HDAC3
als_genetic_variants -->|"implicated_in"| ALS
als_genetic_variants -->|"implicated_in"| ALS
ANXIETY["ANXIETY"]
als_genetic_variants -->|"causes"| ANXIETY
style als_genetic_variants fill:#ef5350,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0
style CUL2 fill:#006494,stroke:#333,stroke-width:1px,color:#e0e0e0
style DES fill:#006494,stroke:#333,stroke-width:1px,color:#e0e0e0
style NOS2 fill:#006494,stroke:#333,stroke-width:1px,color:#e0e0e0
style KCNJ6 fill:#006494,stroke:#333,stroke-width:1px,color:#e0e0e0
style ALS fill:#006494,stroke:#333,stroke-width:1px,color:#e0e0e0
style ICAM1 fill:#006494,stroke:#333,stroke-width:1px,color:#e0e0e0
style HDAC3 fill:#006494,stroke:#333,stroke-width:1px,color:#e0e0e0
style ANXIETY fill:#006494,stroke:#333,stroke-width:1px,color:#e0e0e0| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||