Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about ampk-protein: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
No summary available yet. View on Wiki →
| Gene Symbol | AMPK |
| Aliases | ampk-protein |
| Protein Family | AMPK family, Ser/Thr protein kinases |
| Subcellular Localization | Cytoplasm, Nucleus (shuttles) |
| Molecular Weight | 62 kDa (α subunit) |
| UniProt ID | [Q9NPJ3](https://www.uniprot.org/uniprot/Q9NPJ3) (α1), [P54646](https://www.uniprot.org/uniprot/P54646) (α2) |
| GeneCards | AMPK |
| Human Protein Atlas | AMPK |
| Associated Diseases | Alzheimer's Disease, Parkinson's Disease |
| Databases | GeneCardsNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
ampk_protein["ampk-protein"]
AMPK["AMPK"]
ampk_protein -->|"regulates"| AMPK
ampk_protein -->|"activates"| AMPK
ampk_protein -->|"activates"| AMPK
ampk_protein -->|"therapeutic_target"| AMPK
ampk_protein -->|"associated_with"| AMPK
MFN1["MFN1"]
ampk_protein -->|"activates"| MFN1
aging["aging"]
ampk_protein -->|"regulates"| aging
ampk_protein -->|"activates"| AMPK
CGAS_STING["CGAS-STING"]
ampk_protein -->|"regulates"| CGAS_STING
TAUOPATHY["TAUOPATHY"]
ampk_protein -->|"regulates"| TAUOPATHY
ampk_protein -->|"protects_against"| AMPK
ampk_protein -->|"activates"| AMPK
style ampk_protein fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0
style AMPK fill:#006494,stroke:#333,stroke-width:1px,color:#e0e0e0
style MFN1 fill:#006494,stroke:#333,stroke-width:1px,color:#e0e0e0
style aging fill:#5d2900,stroke:#333,stroke-width:1px,color:#e0e0e0
style CGAS_STING fill:#006494,stroke:#333,stroke-width:1px,color:#e0e0e0
style TAUOPATHY fill:#006494,stroke:#333,stroke-width:1px,color:#e0e0e0| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||