entity

axonal_RNA_transport

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about axonal_RNA_transport: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

2Connections
1Hypotheses
1Analyses
1Outgoing
1Incoming

Wiki Pages (20)

Knowledge base pages for this entity

nimodipine-als

clinical_trial · 5778 words

HNRNPA2B1 Protein

protein · 5015 words

Wallerian Degeneration

mechanism · 3587 words

amiloride-als

clinical_trial · 3477 words

Riluzole ALS Trials

clinical · 3263 words

Outgoing (1)

TargetRelationTypeStr
synaptic_functionmaintainspathway0.80

Incoming (1)

SourceRelationTypeStr
HNRNPA2B1mediatesgene0.80

Targeting Hypotheses (1)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
Axonal RNA Transport Reconstitution 0.446 neurodegeneration RNA binding protein dysregulation across

Mentioning Analyses (1)

Scientific analyses that reference this entity

RNA binding protein dysregulation across ALS FTD and AD

neurodegeneration | 2026-04-01 | 7 hypotheses Top: 0.490

Related Papers (20)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
SIRT6-regulated macrophage efferocytosis epigenetically controls inflammation re [PMID:36593966] Li B, Xin Z, Gao S, Li Y, Guo S, Fu Y, X Theranostics 2023 1
Multisystem proteinopathy: Where myopathy and motor neuron disease converge. [PMID:33145792] Korb MK, Kimonis VE, Mozaffar T Muscle Nerve 2021 1
The role of m6A modification in the biological functions and diseases. [PMID:33611339] Jiang X, Liu B, Nie Z, Duan L, Xiong Q, Signal Transduct Target Ther 2021 1
Tumor-derived exosomal miR-934 induces macrophage M2 polarization to promote liv [PMID:33213490] Senlin Zhao, Yushuai Mi, Bingjie Guan, B Journal of hematology & oncolo 2020 1
Rare Inherited forms of Paget's Disease and Related Syndromes. [PMID:30756140] Ralston SH, Taylor JP Calcif Tissue Int 2019 1
A LNK-CBL-HNRPA2B1-GPX4 signaling axis mediates dopaminergic neuron vulnerabilit [PMID:41616574] ["Liu Z", "Wang R", "Shen M", "Lan X", " Redox biology 2026 0
Human papillomavirus 16 E6 oncoprotein promotes up-regulation of RNA-binding pro [PMID:41725810] ["Cerasuolo A", "Pecchillo Cimmino T", " Frontiers in microbiology 2026 0
Molecular recognition and induced dimerization of hnRNP A2/B1 truncations by G-q [PMID:41888191] ["Shahatibieke D", "Tang X", "Zheng X", Scientific reports 2026 0
Coordinated Post-Transcriptional Regulation facilitates PD-L1 protein production [PMID:41936857] Chen R, Rajasekaran S, Xing X, Zhang Q, Cancer Lett 2026 0
LncRNA 4930544M13Rik-201 regulates CACNA2D1 expression via interacting with hnRN [PMID:41864512] Fang Z, Liu F, Tang Q, Liu Y, Peng Y, Zh Brain research bulletin 2026 0
Comparative Binding Analysis by Computational Methods and Quartz Crystal Microba [PMID:41728844] ["Volkova O", "Serova A", "Kravtsov V", Journal of chemical informatio 2026 0
Functional Variants of the RAD51 Gene Contribute to Susceptibility to Non-Syndro [PMID:41918261] Guo S, Guo T, Xu Y, Chen R, Wang X Orthodontics & craniofacial re 2026 0
Ligand-specific conformational dynamics and interaction landscapes of hnRNPA2B1 [PMID:41853685] Zhou Z, Li Y, Yang P, Zhu R, Li J, Wu B, Current research in structural 2026 0
Neddylation-Mediated hnRNPA2B1 Degradation Aggravates Retinal Endothelial Cell D [PMID:41773772] Chen TR, Zhou JX, Hou YR, Zhang YN, Li C Investigative ophthalmology & 2026 0
Mechanistic studies on HNRNPA2B1 suggest binding but not selective recognition o [PMID:41662154] ["Park R", "Demny M", "Miller L", "Pedra RNA biology 2026 0
Network medicine modeling of the m⁶A regulatory landscape identifies a KLF6-WTAP [PMID:41787499] Xu C, Zhou Z, Lin Y, Zhang S, Cai S, Li Journal of translational medic 2026 0
Integrative transcriptome-wide association analyses reveal PRKCG-linked GABAergi [PMID:41507195] ["Jin Y", "Cao Y", "Ma W", "Li R", "Li Y Nature communications 2026 0
The Intersection of m6A Methylation and Immune Response in PCOS: A Bioinformatic [PMID:41725222] ["Xu W", "Shi L", "Lu A", "Cui L", "Qian Immunity, inflammation and dis 2026 0
Expression, purification, and biophysical characterization of liquid-liquid phas [PMID:41297573] ["Dur\u00e1n-Armenta L", "Meszaros A", " Protein expression and purific 2026 0
Interaction of tau with HNRNPA2B1 and N6-methyladenosine RNA mediates the progre [PMID:34453888] Jiang L, Lin W, Zhang C, Ash PEA, Verma Molecular cell 2021 0