biomarker 1,481 words KG: ent-prot-1e3aff6a
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tau-oligomers

🔬 Protein Info
Gene Symbolent-prot-1e3aff6a
T-Olig (Oligomeric tau)Soluble toxic species (50-250 kDa)
T-Phos (Phosphorylated tau)Hyperphosphorylated monomers (50-70 kDa)
T-Fibr (Fibrillar tau)Insoluble NFTs (neurofibrillary tangles)
J-ADNI cohortCSF tau oligomers showed 80% sensitivity, 82% specificity for AD diagnosis [@takeda2024]
KBASE studyBlood tau oligomers demonstrated AUC 0.82 in Korean population [@kim2024]
CANDI consortiumCSF tau oligomers validated in Chinese AD patients [@zhang2024]
KG Connections7 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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