| Gene Symbol | ent-gene-93d534b4 |
| Coiled-coil domains (CC1, CC2) | Mediate protein-protein interactions |
| WD40 repeat domain | Beta-propeller for protein binding |
| LIR motif (LC3-interacting region) | Binds ATG8/LC3 family proteins |
| Beclin-1 binding domain | Direct interaction with Beclin-1 |
| Beclin-1 | Primary interaction, enhances class III PI3K activity |
| ATG14L (Barkor) | Targets PI3K complex to isolation membrane |
| VPS34 (PIK3C3) | Catalytic subunit of PI3K complex |
| ULK1 | Upstream kinase that phosphorylates AMBRA1 |
| TRAF6 | E3 ubiquitin ligase for AMBRA1 activation |
| KG Connections | 4 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
No AI portrait yet
No comments yet. Be the first to comment!