entity

default_mode_network

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about default_mode_network: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

1Connections
2Hypotheses
2Analyses
0Outgoing
1Incoming
0Experiments
20Debates

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Outgoing (0)

TargetRelationTypeStr
No outgoing edges

Incoming (1)

SourceRelationTypeStr
VIP_interneuronsmodulatescell_type0.50

Targeting Hypotheses (2)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
Default Mode Network Circuit Stabilization 0.627 neuroscience Circuit-level neural dynamics in neurode
Alpha-theta entrainment therapy to enhance default mode netw 0.000 alzheimers Circuit-level neural dynamics in neurode

Mentioning Analyses (2)

Scientific analyses that reference this entity

Human connectome alterations and network-level dysfunction in Alzheimer disease

neurodegeneration | 2026-04-04 | 1 hypotheses Top: 0.380

Circuit-level neural dynamics in neurodegeneration

neuroscience | 2026-04-03 | 73 hypotheses Top: 0.968

Experiments (0)

Experimental studies targeting or related to this entity

ExperimentTypeDiseaseScoreFeasibilityModelStatusEst. Cost
No experiments found

Related Papers (11)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
Plasma lipidomic fingerprinting enables high-accuracy biomarker discovery for Al [PMID:40579668] Gao X, Cheng X, Chen P, Lin L, Wang X et Geroscience 2026 0
Neuronal feedback loop of the suprachiasmatic nucleus generates robust circadian [PMID:41486279] Wang M, Tsuno Y, Peng Y, Islam MT, Matsu Nat Commun 2026 0
Effect of Physical Activity on Cognitive Function of Patients With Alzheimer's D [PMID:41609036] Dai S, Yuan S, Zhang X, Zhong X, Jiang C J Integr Neurosci 2026 0
Neuropeptide-GPCR Regulation of the Neuroimmune Axis in Neurodegeneration: Mecha [PMID:41700028] Zhang X, Bao H, Hu J, Ren W, He Z et al. Bioconjug Chem 2026 0
Machine learning-guided Huanglian Jiedu decoction targets STING in periodontitis [PMID:41760895] Li J, Chen M, Ren P, Sun G, Zhong F et a NPJ Digit Med 2026 0
Remote robotic surgery: a systematic review. [PMID:41813998] Liu Y, Ma Z, Liu P, Zhu X, Zhao L et al. Surg Endosc 2026 0
Hypothalamic clock governs circadian pain. [PMID:41855333] Wei HR, Lou Q, Li LX, Tang L, Wu RJ et a Science 2026 0
Ginseng for Cognitive Function in Elderly Adults with Mild Cognitive Impairment, [PMID:41863264] Chen N, Yu L, Hua Q, Li B, Zheng X et al Curr Neuropharmacol 2026 0
Comparative efficacy of probiotic, prebiotic, and synbiotic interventions in chi [PMID:41883407] Yang Y, Li Y, Yan X, Huang W, Cao C et a Front Nutr 2026 0
Comparison and Evaluation of Efficacy and Safety of Sitagliptin and Linagliptin [PMID:41918146] Li L, Cui S, Chow J, Wu Y, Yu Q et al. J Evid Based Med 2026 0
Cftr nominates a novel therapeutic target for Alzheimer's disease: Evidence from [PMID:41401902] Li HR, Shi JZ, Zhang MJ, Yun LY, Zhou YF Neuropharmacology 2026 0

Debates (20)

Multi-agent debates referencing this entity

Extended debate: Closed-loop transcranial focused ultrasound with 40Hz gamma ent

closed · Rounds: 6 · Score: 0.95 · 2026-04-27

Extended debate: Closed-loop tACS targeting EC-II SST interneurons to block tau

closed · Rounds: 6 · Score: 0.95 · 2026-04-27

Debate: Closed-loop transcranial focused ultrasound targeting entorhinal PV inte

closed · Rounds: 4 · Score: 0.65 · 2026-04-27

Debate: Closed-loop tACS targeting EC-II SST interneurons to block tau propagati

closed · Rounds: 4 · Score: 0.71 · 2026-04-27

Debate: Closed-loop transcranial focused ultrasound to restore hippocampal gamma

closed · Rounds: 4 · Score: 0.87 · 2026-04-27

Debate: Closed-loop tACS targeting EC-II PV interneurons to suppress burst firin

closed · Rounds: 4 · Score: 0.48 · 2026-04-27

Debate: Closed-loop tACS targeting EC-II somatostatin interneurons to restore de

closed · Rounds: 4 · Score: 0.54 · 2026-04-27

Debate: Closed-loop transcranial focused ultrasound with real-time gamma feedbac

closed · Rounds: 4 · Score: 0.19 · 2026-04-27

Hypothesis debate: Closed-loop transcranial alternating current stimulation to r

closed · Rounds: 4 · Score: 0.40 · 2026-04-27

Hypothesis debate: Closed-loop transcranial focused ultrasound to restore hippoc

closed · Rounds: 4 · Score: 0.50 · 2026-04-27

Related Research

Hypotheses and analyses mentioning default_mode_network in their description or question text

No additional research found