gene

KCNK9

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about KCNK9: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

5Connections

0Hypotheses

0Analyses

2Outgoing

3Incoming

0Experiments

0Debates

Summary

KCNK9 (TASK-3) two-pore domain potassium channel implicated in neurodegenerative diseases including Alzheimer's, Parkinson's, and ALS

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🧬 Gene Info

Gene Symbol	KCNK9
Full Name	TASK-3 (Two-pore domain potassium channel)
Aliases	TASK-3
Chromosome	8q24.22
Protein Type	Channel
Function	is a member of the two-pore domain potassium channel family.
Primary Expression	Brain (cortex, thalamus, hippocampus), peripheral tissues
Molecular Weight	37 kDa
Exons	5
UniProt ID	Q9NPC2
NCBI Gene ID	51302
Ensembl ID	ENSG00000149402
OMIM	607366
GeneCards	KCNK9
Human Protein Atlas	KCNK9
Associated Diseases	Alzheimer's Disease, Parkinson's Disease, Neurodevelopmental disorders
KG Connections	5 knowledge graph edges
Databases	GeneCards HPA STRING

🔮 Predicted Structure: KCNK9 — AlphaFold Q9NPC2 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

KCNK9 Gene

gene · 3011 words

→

KCNK9 Protein

protein · 772 words

→

Pathway Diagram

graph TD
    KCNK9["KCNK9"]
    TASK_3["TASK-3"]
    KCNK9 -->|"associated with"| TASK_3
    TASK_1["TASK-1"]
    KCNK9 -->|"associated with"| TASK_1
    KCNK9 -->|"modulates"| TASK_3
    neurodegeneration["neurodegeneration"]
    KCNK9 -->|"implicated in"| neurodegeneration
    halothane["halothane"]
    halothane -->|"activates"| KCNK9
    thyrotropin_releasing_hormone["thyrotropin-releasing hormone"]
    thyrotropin_releasing_hormone -->|"inhibits"| KCNK9
    style KCNK9 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0

Outgoing (2)

Target	Relation	Type	Str
TASK-3	associated_with	protein	0.80
TASK-1	associated_with	protein	0.80

Incoming (3)

Source	Relation	Type	Str
genes-kcnk9	linked_to	wiki	1.00
halothane	activates	chemical	0.80
thyrotropin-releasing hormone	inhibits	chemical	0.80

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning KCNK9 in their description or question text

No additional research found