Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about kynurenine pathway: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
Knowledge base pages for this entity
| Target | Relation | Type | Str |
|---|---|---|---|
| aging | associated_with | phenotype | 0.90 |
| Alzheimer's disease | associated_with | disease | 0.70 |
| Source | Relation | Type | Str |
|---|---|---|---|
| IDO | activates | enzyme | 0.90 |
| TDO | activates | enzyme | 0.90 |
| Indoleamine 2,3-Dioxygenase | regulates | enzyme | 0.85 |
| INFLAMMATION | activates | phenotype | 0.65 |
| CYTOKINES | activates | phenotype | 0.65 |
| NEURODEGENERATION | inhibits | disease | 0.65 |
| MELATONIN | activates | drug | 0.65 |
| OXIDATIVE STRESS | regulates | process | 0.50 |
| MULTIPLE SCLEROSIS | associated_with | disease | 0.45 |
| HUNTINGTON'S DISEASE | associated_with | disease | 0.45 |
| PARKINSON'S DISEASE | associated_with | disease | 0.45 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||