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general 2,389 words KG: GLUTAMATE
Contents

glutamate

🔬 Protein Info
Gene SymbolGLUTAMATE
Associated DiseasesCOGNITIVE DECLINE, EPILEPSY, EXCITOTOXICITY, FERROPTOSIS, GLUTAMATE EXCITOTOXICITY, GLYCOLYSIS
Known Drugs/CompoundsKETAMINE
InteractionsPARKIN, PINK1, PTEN, UBIQUITIN, AMPK, TAU
KG Connections505 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (30)

p38α Inhibitor and PRMT1 Activator Combination to Restore Ph
Score: 0.61TREM2-Mediated Astrocyte-Microglia Crosstalk in Neurodegener
Score: 0.61Direct Toxicity Hypothesis: β-Amyloid Directly Impairs Choli
Score: 0.60Astrocyte-Intrinsic NLRP3 Inflammasome Activation by Alpha-S
Score: 0.60TREM2-Mediated Astrocyte-Microglia Cross-Talk in Neurodegene
Score: 0.59

Related Analyses (29)

Metabolomic signatures of neurodegeneration and energy metab
neurodegeneration · failedTDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archivedAstrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archivedBlood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archivedMicroglia-astrocyte crosstalk amplification loops in neurode
neurodegeneration · archived

Related Experiments (8)

Macroautophagy Dysfunction in PD - Experiment Design
clinical · proposed · Score: 0.46Stress-induced depression model sleep architecture analysis
validation · proposed · Score: 0.90Electrophysiological analysis of mPFC-vlPAG synaptic transmi
exploratory · proposed · Score: 0.85Pathway analysis of aminophylline effects on neuronal signal
exploratory · proposed · Score: 0.70s:** - Test MCU overexpression specifically in layer II neur
falsification · proposed · Score: 0.46

See Also (5)

Packard Center for ALS Research
institution · KG edge: associated_withAlzheimer Indonesia
institution · KG edge: activatesGPX4 Gene - Glutathione Peroxidase 4
gene · KG edge: co_discussedadra2b Gene
gene · KG edge: expressed_inacetylcholine
general · KG edge: co_discussed

Knowledge Graph (12 edges)

GLUTAMATE inhibits AXONS
GLUTAMATE causes EXCITOTOXICITY
GLUTAMATE co_discussed GPX4
GLUTAMATE co_discussed MITOCHONDRIA
GLUTAMATE co_discussed OPTN
GLUTAMATE co_discussed PINK1
GLUTAMATE co_discussed NMDA
GLUTAMATE co_discussed NEUROINFLAMMATION
GLUTAMATE co_discussed GLUTAMATERGIC
GLUTAMATE co_discussed SYNAPSE
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