| Gene Symbol | ent-gene-8c4c3123 |
| Irisin | Cleaved from FNDC5, crosses the blood-brain barrier, enhances hippocampal function[@martinez2022] |
| Cathepsin B | Released during endurance exercise, increases BDNF expression in the hippocampus |
| BDNF | Directly released from muscle cells in response to contraction, contributes to circulating levels[@cacciola2020] |
| Lactate | Acts as a signaling molecule, enhances neuronal plasticity and memory formation[@yuan2023] |
| BAIBA (β-aminoisobutyric acid) | Reduces inflammation and improves insulin sensitivity |
| KG Connections | 10 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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