cellular_component

mitochondrial membrane

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about mitochondrial membrane: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

2Connections
1Hypotheses
1Analyses
0Outgoing
2Incoming
0Experiments
1Debates

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Pathway Diagram

graph TD
    mitochondrial_membrane["mitochondrial membrane"] -->|"found in"| neurons["neurons"]
    style neurons fill:#1a2a3a,stroke:#4fc3f7,stroke-width:1px,color:#fff
    mitochondrial_membrane["mitochondrial membrane"] -->|"found in"| neural_stem_cells["neural stem cells"]
    style neural_stem_cells fill:#1a2a3a,stroke:#4fc3f7,stroke-width:1px,color:#fff
    mitochondrial_membrane["mitochondrial membrane"] -->|"involved in"| ferroptosis["ferroptosis"]
    style ferroptosis fill:#1a2a3a,stroke:#81c784,stroke-width:1px,color:#fff
    mitochondrial_membrane["mitochondrial membrane"] -->|"involved in"| PI3K_AKT_mTOR_signaling["PI3K-AKT-mTOR signaling"]
    style PI3K_AKT_mTOR_signaling fill:#1a2a3a,stroke:#81c784,stroke-width:1px,color:#fff
    mitochondrial_membrane["mitochondrial membrane"] -->|"involved in"| mitochondrial_dynamics["mitochondrial dynamics"]
    style mitochondrial_dynamics fill:#1a2a3a,stroke:#81c784,stroke-width:1px,color:#fff
    mitochondrial_membrane["mitochondrial membrane"] -->|"involved in"| unfolded_protein_response["unfolded protein response"]
    style unfolded_protein_response fill:#1a2a3a,stroke:#81c784,stroke-width:1px,color:#fff
    mitochondrial_membrane["mitochondrial membrane"] -->|"found in"| endothelial_cells["endothelial cells"]
    style endothelial_cells fill:#1a2a3a,stroke:#4fc3f7,stroke-width:1px,color:#fff
    ROS["ROS"] -->|"activates"| mitochondrial_membrane["mitochondrial membrane"]
    style ROS fill:#1a2a3a,stroke:#ce93d8,stroke-width:1px,color:#fff
    PINK1["PINK1"] -->|"activates"| mitochondrial_membrane["mitochondrial membrane"]
    style PINK1 fill:#1a2a3a,stroke:#ce93d8,stroke-width:1px,color:#fff
    PRKN["PRKN"] -->|"activates"| mitochondrial_membrane["mitochondrial membrane"]
    style PRKN fill:#1a2a3a,stroke:#ce93d8,stroke-width:1px,color:#fff
    phosphatidylethanolamine["phosphatidylethanolamine"] -->|"expressed in"| mitochondrial_membrane["mitochondrial membrane"]
    style phosphatidylethanolamine fill:#1a2a3a,stroke:#4fc3f7,stroke-width:1px,color:#fff
    ATP["ATP"] -->|"activates"| mitochondrial_membrane["mitochondrial membrane"]
    style ATP fill:#1a2a3a,stroke:#ce93d8,stroke-width:1px,color:#fff
    style mitochondrial_membrane fill:#006494,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0,font-weight:bold

Outgoing (0)

TargetRelationTypeStr
No outgoing edges

Incoming (2)

SourceRelationTypeStr
phosphatidylethanolamineexpressed_incompound0.90
TDP-43disruptsprotein0.70

Targeting Hypotheses (1)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
Phosphatidylserine Decarboxylase (PISD) Restoration to Corre 0.342 lipidomics Lipid metabolism dysregulation in Alzhei

Mentioning Analyses (1)

Scientific analyses that reference this entity

How does chronic cGAS/STING activation downstream of TDP-43 contribute to progre

neuroinflammation | 2026-04-07 | 8 hypotheses Top: 0.821

Experiments (0)

Experimental studies targeting or related to this entity

ExperimentTypeDiseaseScoreFeasibilityModelStatusEst. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found

Debates (1)

Multi-agent debates referencing this entity

The study identifies cGAS/STING activation as a consequence of TDP-43-mediated m

closed · Rounds: 4 · Score: 0.73 · 2026-04-21

Related Research

Hypotheses and analyses mentioning mitochondrial membrane in their description or question text

No additional research found