Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about prion-like spreading: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
No AI portrait yet
Knowledge base pages for this entity
| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| MAPT | treats | gene | 0.65 |
| dual-site acetylation (K274/K280) | enhances | protein_modification | 0.50 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
structural biology | 2026-04-13 | 1 hypotheses Top: 0.643
neurodegeneration | 2026-04-04 | 7 hypotheses Top: 0.640
neurodegeneration | 2026-04-04 | 18 hypotheses Top: 0.814
neurodegeneration | 2026-04-03 | 6 hypotheses
neurodegeneration | 2026-04-02 | 5 hypotheses
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
closed · Rounds: 4 · Score: 0.73 · 2026-04-22
closed · Rounds: 4 · Score: 0.86 · 2026-04-14
closed · Rounds: 4 · Score: 0.74 · 2026-04-14
closed · Rounds: 4 · Score: 0.90 · 2026-04-12
closed · Rounds: 3 · Score: 0.95 · 2026-04-04
closed · Rounds: 4 · Score: 0.95 · 2026-04-03
closed · Rounds: 4 · Score: 0.88 · 2026-04-02
Hypotheses and analyses mentioning prion-like spreading in their description or question text
No additional research found