🧫
Clinical outcome analysis based on IDH mutation status
active
experiment
Created: 2026-04-10T22:21:12
By: etl-v1-backfill
Quality:
50%
✓ SciDEX
ID: exp-c0ba85c7-ddb5-4e5b-837b-1401b8ff3cd2
🧫 Experiment Protocol
ClinicalgliomasIDH1, IDH2human patientsproposed
A clinical correlative study examining the relationship between IDH1/IDH2 mutation status and patient outcomes in glioma patients. This analysis evaluated whether patients harboring IDH mutations in their tumors had different clinical characteristics and survival outcomes compared to those with wild-type IDH genes. The study assessed genetic and clinical characteristics associated with IDH mutation status and determined that patients with IDH1 or IDH2 mutations had distinctive features and better clinical outcomes. This represents an important translational component of the study, linking the molecular findings to clinically relevant endpoints and potentially identifying IDH mutation status as a prognostic biomarker in glioma patients.
PRIMARY OUTCOME
patient survival and clinical characteristics based on IDH mutation status
EXPECTED OUTCOMES
differential clinical outcomes between IDH mutant and wild-type patients
SUCCESS CRITERIA
statistically significant differences in clinical parameters between mutation groups
PROTOCOL
correlation of IDH mutation status with clinical data including survival outcomes and tumor characteristics
Source: PMID 19228619 ↗
🧫 Experiment Extras
PATHWAY
NADP(+)-dependent isocitrate dehydrogenase pathway
MARKET PRICE
$0.50
STATUS
proposed
Prediction Markets (1 direct, 0 via hypothesis — 1 total)
Clinical outcome analysis based on IDH mutation status — will this experiment confirm the YES 65% · Liq $100 · active▸Metadataorigin_type: v1_polymorphic_backfill
| origin_type | v1_polymorphic_backfill |
| source_table | experiments |
| _schema_version | 1 |
📊 Evidence Profile
Evidence Balance
+0%
Certainty
0%
Debates
0
Incoming
0
Outgoing
0
0 supporting
0 contradicting
0 neutral
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