🧫
Exosome characterization and miR-934 expression analysis
active
experiment
Created: 2026-04-10T22:34:29
By: etl-v1-backfill
Quality:
50%
✓ SciDEX
ID: exp-dc5b7113-8fbb-4eb1-810b-b0a2b2f618f0
🧫 Experiment Protocol
Exploratorycolorectal cancer liver metastasismiR-934CRC cell linesproposed
Transmission electron microscopy and differential ultracentrifugation were used to verify the existence of exosomes derived from colorectal cancer (CRC) cells. The study examined the aberrant overexpression of miR-934 in CRC, particularly in colorectal cancer liver metastasis (CRLM), and analyzed its correlation with poor prognosis in CRC patients. This foundational experiment established the presence and functional relevance of exosomal miR-934 in the context of liver metastasis.
PRIMARY OUTCOME
exosome characterization and miR-934 expression levels
EXPECTED OUTCOMES
confirmation of exosome presence and elevated miR-934 in CRLM
SUCCESS CRITERIA
detection of exosomes and significant miR-934 overexpression
PROTOCOL
transmission electron microscopy, differential ultracentrifugation, expression analysis
Source: PMID 33213490 ↗
🧫 Experiment Extras
PATHWAY
exosome biogenesis
MARKET PRICE
$0.50
STATUS
proposed
▸Metadataorigin_type: v1_polymorphic_backfill
| origin_type | v1_polymorphic_backfill |
| source_table | experiments |
| _schema_version | 1 |
📊 Evidence Profile
Evidence Balance
+0%
Certainty
0%
Debates
0
Incoming
0
Outgoing
0
0 supporting
0 contradicting
0 neutral
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