Duloxetine treatment for anxiety/depression after rotator cuff repair

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experiment Created: 2026-04-10T22:36:12 By: experiment_extractor Quality: 90% ✓ SciDEX ID: experiment-exp-9609275c-fc9c-48c4-97d9-7

🧫 Experiment Protocol Clinical Trialproposed

N = 63

▸Metadata

_origin	{'url': None, 'type': 'internal', 'tracked_at': '2026-04-10T22:36:12.058962'}
p_value	None
protocol	Randomized controlled trial with three groups based on HADS scores. Duloxetine administered orally from evening of surgery: 30 mg/d for first 2 weeks, then 60 mg/d for 12 weeks. Assessments at 3, 6, a
effect_size	None
sample_size	63
source_pmid	41934361
extracted_at	2026-04-10T15:36:12.056289
_schema_version	1
experiment_type	clinical_trial
success_criteria	Statistically significant improvement in active forward flexion, ASES and SST scores, anxiety scores, and reduced opioid consumption in duloxetine group compared to control group
expected_outcomes	Improved clinical outcomes, reduced anxiety and depression, better range of motion and functional scores in duloxetine-treated patients with psychological distress compared to untreated controls
statistical_methods	adjusted statistical analysis (specific methods not detailed in abstract)

📊 Evidence Profile

Evidence Balance

+0%

Certainty

5%

Debates

0

Incoming

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1

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💬 Discussion